The state of Osun bears a significant NTD burden, with four of the five most common NTDs prevalent in the State. The State has a particular high burden of Onchocerciasis (River blindness with 28 LG endemicity), Lymphatic Filariasis (elephantiasis with 27 LG. endemicity), and Schistosomiasis and Soil-transmitted helminths (intestinal worms). These NTDs primarily impact the poor rural communities that make up more than 50 percent of the population.